352Clinical and molecular characteristics of NDM-1 harboring Multi-Drug Resistant Gram Negative Bacteria at Carilion Medical Center
نویسندگان
چکیده
352. Clinical and molecular characteristics of NDM-1 harboring MultiDrug Resistant Gram Negative Bacteria at Carilion Medical Center Ekta Bansal, MD; Thomas Kerkering, MD; Charles Schleupner, MD; Ritesh Kohli, MD; Anthony Baffoe, MBChB; Endang Purwantini, PhD; Biswarup Mukhopadhyay, PhD; Jayasimha Rao, PhD; Virginia Tech Carilion School of Medicine, Roanoke, VA; Infectious Diseases, Carilion Clinic Virginia Tech Carilion School of Medicine, Roanoke, VA; Internal Medicine, Virginia Tech/Carilion School of Medicine, Roanoke, VA; Biochemistry, Virginia Tech, Blacksburg, VA; Biochemisstry, Virginia Tech, Blacksburg, VA; Internal Medicine/Section of Infectious Diseases, Virginia Tech Carilion School of Medicine, Roanoke, VA
منابع مشابه
Emergence of Imipenem Resistance and Presence of Metallo--Lactamases Enzymes in Multi Drug Resistant Gram Negative Bacilli Isolated from Clinical Samples in Kerman, 2007-2008
Background & Aims: Imipenem is a member of Carbapenem with stability against most -lactamases .It is of particular use in the treatment of infections associated with drug resistant gram negative bacteria harboring ESBL and AmpC genes. The aim of this study was to determine the imipenem resistance in gram negative bacteria causing nosocomial infections and the presence of metallo--lactamases (MB...
متن کاملFrequency of Multi-Drug Resistance (MDR) in Gram Negative Bacteria from Urinary Infection in Gorgan, 2011-12
Abstract Background and objective: The periodic evaluation of antimicrobial activity of different antibiotic is essential because antibiotic sensitivity pattern may also changed during short courses. The aim of this study was to assess the frequency of Multi-drug Resistance (MDR) in Gram negative uropathogens. Material and Methods: This study was conducted on 111 gram negative uropatho...
متن کاملEmergence of Acinetobacter pittii Harboring New Delhi Metallo-β-Lactamase Genes in Daejeon, Korea
Carbapenemase production has been reported worldwide in gram-negative bacteria, including Acinetobacter species. We detected carbapenemase-producing Acinetobacter pittii in clinical isolates in Daejeon, Korea. Twenty-one ertapenem-resistant A. pittii isolates screened with a disk diffusion method were characterized by using the Epsilon test, four multiplex PCR assays, and a multilocus sequence ...
متن کاملEfficacy of Amikacin and Imipenem Against Multi-Drug Resistant Gram-Negative Bacteria Isolated From Wound Infections
Background and Objective: Gram-negative pathogens are considered the common cause of wound infections associated with increased mortality and morbidity rates. Antibiotics combination has been used to overcome this problem. Aims: In this study, we identify Gram-negative pathogens found in wound infections and assess the in-vitro efficacy of a combination of amikacin and imipenem against the resi...
متن کاملDetection of co-harboring OXA-58 and NDM-1carbapenemase producing genes resided on a same plasmid from an Acinetobacter pittii clinical isolate in China
Objective(s): Acinetobacter pittii has become an emerging opportunistic noscomial pathogen worldwide with multi-drug resistance. In the present study, an A. pittii strain was isolated from bronchoalveolar lavage fluid sample harboring both OXA-58 and NDM-1carbapenemase producing genes. The mechanisms of carbapenem resistance of the A. pittii strain was investigated.Materials and Methods: Carbap...
متن کامل